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. 2019 Oct 25;7:276. doi: 10.3389/fbioe.2019.00276

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Copyright © 2019 Sherwood, Boazak, Feola, Parker, Ethier and Overby.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of the measurements of ocular compliance between the two methods (A,B) and between contralateral eyes (C,D). (A) The reference ocular compliance, ϕ_r, calculated by the Step Response Method plotted against that calculated by the Discrete Volume Method. Each data point represents an individual eye (N = 24) from 12 mice (separate colours), with filled vs. open circles identifying the two eyes from a given mouse. Shaded regions surrounding each data point represent the 95% confidence intervals on each estimate of ϕ_r. Figure S4 shows a Bland-Altman plot of the same data. (B) The 95% confidence intervals on the estimated values of ϕ_r shown in panel a, using the same colour scheme as (A). (C,D) A comparison of ϕ_r between contralateral eyes measured using the Discrete Volume Method (C) and Step Response Method (D). Each data point represents an individual mouse, with ϕ_r from contralateral eyes plotted on each axis. Shading represents 95% confidence intervals. The colour scheme is the same as in (A,B). The unity line, representing exact parity, is shown in black for each panel.