Table 2.

Adverse events related to interferon therapy

Study ID	Adverse events listed	Percentage of patients
Porres 1989	Flu‐like symptoms Weight loss Leukopoenia Thrombocytopoenia	100 40 30 40
Rosina 1989	Flu‐like symptoms Transient hair loss Herpes labialis Granuloopoenia	100 33 25 67
Rosina 1991	Flu‐like symptoms Fatigue Weight loss Alopaecia Nausea/Anorexia Vomiting Impaired consciousness Rhinorrhea	100 100 100 17 35 6 3 3
Farci 1994	Flu‐like symptoms Asthenia Alopaecia Anemia	100 50 43 4
Madejon 1994	Asthenia Anorexia Fever Weight loss Arthralgias Hair loss Headache Itching	56 50 47 47 41 38 38 12
Gaudin 1995	Flu‐like symptoms Leukopoenia Thrombocytopoenia Hyperthyroidism Death (by suicide)	100 100 100 10 10