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2 Adverse events requiring dose modification or termination of interferon therapy
| Study ID | Events* | Total number of participants | % |
| Porres 1989 | 0 | 10 | 0 |
| Rosina 1989 | 0 | 12 | 0 |
| Rosina 1991 | 16 | 31 | 51.6 |
| Farci 1994 | 2 | 28 | 7.1 |
| Gaudin 1995 | 4 | 11 | 36.4 |
| Madejon 1994 | 7 | 32 | 21.9 |
| Total | 29 | 124 | 23.4 |
Total number of participants are the patients who received interferon. Events represent number of participants experiencing adverse events requiring dose modification or termination of therapy
