Study	Reason for exclusion
Agras 1991	Randomization was flawed and the groups were not comparable (Personal communication from Dr Agras on Oct 14, 2003).
Ba 1999	Although 3 arms had been planned (pharmacotherpay alone, pharmacotherapy plus CBT, pharmacotherapy plus CBT plus psychodynamic therapy), only the last two were successfully completed. Moreover, pharmacotherapy always consisted of SSRI plus alprazolam.
Chambless 1979	Flooding versus Flooding + barbiturate
Cox 1988	Randomized comparison between high serum level vs low serum level of imipramine, combined with behavior therapy
Lipsedge 1973	No operational diagnostic criteria used. Iproniazid, though with MAO inhibiting effect, is not a widely recognized antidepressant.
Solyom 1981	Although the overall study design appears to satisfy the inclusion criteria of this systematic review, the authors did not separately report the results for agoraphobia and social phobia. The original author was contacted but could not provide separate data for patients with agoraphobia.