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. 2019 Oct 25;10:1249. doi: 10.3389/fphar.2019.01249

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Copyright © 2019 Kundap, Choo, Kumari, Ahmed, Othman and Shaikh

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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T-maze tracking pattern and behavior analysis of embelin treatment against pentylenetetrazole (PTZ) induced seizures and cognitive dysfunction. (A) represents the T-maze tracking pattern of locomotor behavior for the control and PTZ treated and EMB treated groups. (B, C) represent the graph plot of the inflection ratio at the 3 h and 24 h T-maze trial. (D, E) represents the time spent in the wrong arm and the total distance traveled by each fish to reach the deepest chamber of T-maze behavior tank. Data are represented as mean ± SEM, n = 8, and statistically analyzed by one-way ANOVA followed by Dunnett’s test *P ≤0.05, **P ≤ 0.01, and ***P ≤ 0.001.