Comparison 2.
Appearance of ascites
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
|---|---|---|---|---|
| 1 All studies | 8 | 582 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.60 [0.47, 0.77] |
| 2 Parenteral nutrition | 4 | 214 | Risk Ratio (M‐H, Random, 95% CI) | 0.65 [0.39, 1.08] |
| 2.1 Medical trials | 2 | 26 | Risk Ratio (M‐H, Random, 95% CI) | 0.23 [0.01, 3.97] |
| 2.2 Surgical trials | 2 | 188 | Risk Ratio (M‐H, Random, 95% CI) | 0.67 [0.39, 1.15] |
| 3 Enteral nutrition | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 3.1 Medical trials | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 3.2 Surgical trials | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 4 Supplements | 4 | 368 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.58 [0.38, 0.87] |
| 4.1 Medical trials | 4 | 368 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.58 [0.38, 0.87] |
| 4.2 Surgical trials | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 5 Medical trials | 6 | 394 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.56 [0.37, 0.84] |
| 5.1 Parenteral nutrition | 2 | 26 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.23 [0.01, 3.97] |
| 5.2 Enteral nutrition | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 5.3 Supplements | 4 | 368 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.58 [0.38, 0.87] |
| 6 Surgical trials | 2 | 188 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.65 [0.48, 0.87] |
| 6.1 Parenteral nutrition | 2 | 188 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.65 [0.48, 0.87] |
| 6.2 Enteral nutrition | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 6.3 Supplements | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 7 Alcoholic hepatitis | 3 | 77 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.62 [0.31, 1.26] |
| 7.1 Parenteral nutrition | 2 | 26 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.23 [0.01, 3.97] |
| 7.2 Enteral nutrition | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 7.3 Supplements | 1 | 51 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.70 [0.34, 1.45] |
| 8 Cirrhosis | 2 | 82 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.72 [0.36, 1.46] |
| 8.1 Parenteral nutrition | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 8.2 Enteral nutrition | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 8.3 Supplements | 2 | 82 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.72 [0.36, 1.46] |
| 9 HCC | 2 | 286 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.53 [0.32, 0.87] |
| 9.1 Parenteral nutrition | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 9.2 Enteral nutrition | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 9.3 Supplements | 2 | 286 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.53 [0.32, 0.87] |
| 10 Abstracts excluded | 7 | 380 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.60 [0.46, 0.79] |
| 10.1 Parenteral nutrition ‐ medical trials | 2 | 26 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.23 [0.01, 3.97] |
| 10.2 Parenteral nutrition ‐ surgical trials | 2 | 188 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.65 [0.48, 0.87] |
| 10.3 Enteral nutrition ‐ medical trials | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 10.4 Enteral nutrition = surgical trials | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 10.5 Supplements ‐ medical trials | 3 | 166 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.54 [0.29, 1.00] |
| 10.6 Supplements ‐ surgical trials | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 11 Surgical trials without transplant | 2 | 188 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.65 [0.48, 0.87] |
| 11.1 Parenteral nutrition | 2 | 188 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.65 [0.48, 0.87] |
| 11.2 Enteral nutrition | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 11.3 Supplements | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 12 Intent to treat ‐ best‐case scenario for intervention | 8 | 626 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.50 [0.39, 0.64] |
| 12.1 Parenteral nutrition ‐ medical trials | 2 | 26 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.23 [0.01, 3.97] |
| 12.2 Parenteral nutrition ‐ surgical trials | 2 | 214 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.52 [0.39, 0.70] |
| 12.3 Enteral nutrition ‐ medical trials | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 12.4 Enteral nutrition ‐ surgical trials | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 12.5 Supplements ‐ medical trials | 4 | 386 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.49 [0.33, 0.73] |
| 12.6 Supplements ‐ surgical trials | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 13 Intent to treat ‐ worst‐case scenario for intervention | 8 | 626 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.81 [0.65, 1.02] |
| 13.1 Parenteral nutrition ‐ medical trials | 2 | 26 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.23 [0.01, 3.97] |
| 13.2 Parenteral nutrition ‐ surgical trials | 2 | 214 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.87 [0.66, 1.15] |
| 13.3 Enteral nutrition ‐ medical trials | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 13.4 Enteral nutrition = surgical trials | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 13.5 Supplements ‐ medical trials | 4 | 386 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.77 [0.53, 1.11] |
| 13.6 Supplements ‐ surgical trials | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |