Comparison 4.
Appearance of gastrointestinal bleeding
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
|---|---|---|---|---|
| 1 All studies | 11 | 783 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.29 [0.85, 1.96] |
| 2 Parenteral nutrition | 1 | 124 | Risk Ratio (M‐H, Fixed, 95% CI) | 2.82 [0.12, 67.80] |
| 2.1 Medical trials | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 2.2 Surgical trials | 1 | 124 | Risk Ratio (M‐H, Fixed, 95% CI) | 2.82 [0.12, 67.80] |
| 3 Enteral nutrition (all medical) | 4 | 180 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.50 [0.78, 2.86] |
| 3.1 Medical trials | 4 | 180 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.50 [0.78, 2.86] |
| 3.2 Surgical trials | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 4 Supplements | 6 | 479 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.08 [0.62, 1.89] |
| 4.1 Medical trials | 5 | 435 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.08 [0.61, 1.91] |
| 4.2 Surgical trials | 1 | 44 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.10 [0.07, 16.43] |
| 5 Medical trials | 9 | 615 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.27 [0.82, 1.94] |
| 5.1 Parenteral nutrition | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 5.2 Enteral nutrition | 4 | 180 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.50 [0.78, 2.86] |
| 5.3 Supplements | 5 | 435 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.08 [0.61, 1.91] |
| 6 Surgical trials | 2 | 168 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.70 [0.23, 12.73] |
| 6.1 Parenteral nutrition | 1 | 124 | Risk Ratio (M‐H, Fixed, 95% CI) | 2.82 [0.12, 67.80] |
| 6.2 Enteral nutrition | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 6.3 Supplements | 1 | 44 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.10 [0.07, 16.43] |
| 7 Alcoholic hepatitis | 1 | 64 | Risk Ratio (M‐H, Fixed, 95% CI) | 2.88 [0.70, 11.87] |
| 7.1 Parenteral nutrition | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 7.2 Enteral nutrition | 1 | 64 | Risk Ratio (M‐H, Fixed, 95% CI) | 2.88 [0.70, 11.87] |
| 7.3 Supplements | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 8 Cirrhosis | 6 | 234 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.01 [0.62, 1.67] |
| 8.1 Parenteral nutrition | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 8.2 Enteral nutrition | 3 | 116 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.16 [0.55, 2.43] |
| 8.3 Supplements | 3 | 118 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.87 [0.45, 1.69] |
| 9 HCC | 2 | 317 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.50 [0.53, 4.26] |
| 9.1 Parenteral nutrition | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 9.2 Eneral nutrition | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 9.3 Supplements | 2 | 317 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.50 [0.53, 4.26] |
| 10 Abstracts excluded | 9 | 491 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.27 [0.76, 2.13] |
| 10.1 Parenteral nutrition ‐ medical trials | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 10.2 Parenteral nutrition ‐ surgical trials | 1 | 124 | Risk Ratio (M‐H, Fixed, 95% CI) | 2.82 [0.12, 67.80] |
| 10.3 Enteral nutrition ‐ medical trials | 3 | 121 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.67 [0.68, 4.10] |
| 10.4 Enteral nutrition ‐ surgical trials | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 10.5 Supplements ‐ medical trials | 4 | 202 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.97 [0.51, 1.84] |
| 10.6 Supplements ‐ surgical trials | 1 | 44 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.10 [0.07, 16.43] |
| 11 Surgical trials without transplant patients (no trials with transplant patients) | 2 | 168 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.70 [0.23, 12.73] |
| 11.1 Parenteral nutrition | 1 | 124 | Risk Ratio (M‐H, Fixed, 95% CI) | 2.82 [0.12, 67.80] |
| 11.2 Enteral nutrition | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 11.3 Supplements | 1 | 44 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.10 [0.07, 16.43] |
| 12 Intent to treat ‐ best‐case scenario for intervention | 11 | 838 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.67 [0.47, 0.97] |
| 12.1 Parenteral nutrition ‐ medical trials | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 12.2 Parenteral nutrition ‐ surgical trials | 1 | 150 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.07 [0.01, 0.49] |
| 12.3 Enteral nutrition ‐ medical trials | 4 | 184 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.26 [0.69, 2.30] |
| 12.4 Enteral nutrition ‐ surgical trials | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 12.5 Supplements ‐ medical trials | 5 | 454 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.70 [0.42, 1.16] |
| 12.6 Supplements ‐ surgical trials | 1 | 50 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.33 [0.04, 2.99] |
| 13 Intent to treat ‐ worst‐case scenario for intervention | 11 | 838 | Risk Ratio (M‐H, Fixed, 95% CI) | 2.14 [1.46, 3.15] |
| 13.1 Parenteral nutrition ‐ medical trials | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 13.2 Parenteral nutrition ‐ surgical trials | 1 | 150 | Risk Ratio (M‐H, Fixed, 95% CI) | 25.0 [1.51, 414.73] |
| 13.3 Enteral nutrition ‐ medical trials | 4 | 184 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.61 [0.85, 3.07] |
| 13.4 Enteral nutrition ‐ surgical trials | 0 | 0 | Risk Ratio (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 13.5 Supplements ‐ medical trials | 5 | 454 | Risk Ratio (M‐H, Fixed, 95% CI) | 1.72 [1.02, 2.88] |
| 13.6 Supplements ‐ surgical trials | 1 | 50 | Risk Ratio (M‐H, Fixed, 95% CI) | 5.0 [0.63, 39.79] |