Comparison 19.
Appearance gastrointestinal bleeding ‐ absolute risk difference (ARD)
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
|---|---|---|---|---|
| 1 All studies | 11 | 783 | Risk Difference (M‐H, Fixed, 95% CI) | 0.02 [‐0.01, 0.06] |
| 2 Parenteral nutrition | 1 | 124 | Risk Difference (M‐H, Fixed, 95% CI) | 0.02 [‐0.03, 0.06] |
| 2.1 Medical trials | 0 | 0 | Risk Difference (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 2.2 Surgical trials | 1 | 124 | Risk Difference (M‐H, Fixed, 95% CI) | 0.02 [‐0.03, 0.06] |
| 3 Enteral nutrition (all medical) | 4 | 180 | Risk Difference (M‐H, Fixed, 95% CI) | 0.08 [‐0.04, 0.19] |
| 3.1 Medical trials | 4 | 180 | Risk Difference (M‐H, Fixed, 95% CI) | 0.08 [‐0.04, 0.19] |
| 3.2 Surgical trials | 0 | 0 | Risk Difference (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 4 Supplements | 6 | 479 | Risk Difference (M‐H, Fixed, 95% CI) | 0.01 [‐0.04, 0.05] |
| 4.1 Medical trials | 5 | 435 | Risk Difference (M‐H, Fixed, 95% CI) | 0.01 [‐0.04, 0.05] |
| 4.2 Surgical trials | 1 | 44 | Risk Difference (M‐H, Fixed, 95% CI) | 0.00 [‐0.12, 0.13] |
| 5 Medical trials | 9 | 615 | Risk Difference (M‐H, Fixed, 95% CI) | 0.03 [‐0.02, 0.07] |
| 5.1 Parenteral nutrition | 0 | 0 | Risk Difference (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 5.2 Enteral nutrition | 4 | 180 | Risk Difference (M‐H, Fixed, 95% CI) | 0.08 [‐0.04, 0.19] |
| 5.3 Supplements | 5 | 435 | Risk Difference (M‐H, Fixed, 95% CI) | 0.01 [‐0.04, 0.05] |
| 6 Surgical trials | 2 | 168 | Risk Difference (M‐H, Fixed, 95% CI) | 0.01 [‐0.03, 0.06] |
| 6.1 Parenteral nutrition | 1 | 124 | Risk Difference (M‐H, Fixed, 95% CI) | 0.02 [‐0.03, 0.06] |
| 6.2 Enteral nutrition | 0 | 0 | Risk Difference (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 6.3 Supplements | 1 | 44 | Risk Difference (M‐H, Fixed, 95% CI) | 0.00 [‐0.12, 0.13] |
| 7 Alcoholic hepatitis | 1 | 64 | Risk Difference (M‐H, Fixed, 95% CI) | 0.17 [‐0.01, 0.35] |
| 7.1 Parenteral Nutrition | 0 | 0 | Risk Difference (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 7.2 Enteral nutrition | 1 | 64 | Risk Difference (M‐H, Fixed, 95% CI) | 0.17 [‐0.01, 0.35] |
| 7.3 Supplements | 0 | 0 | Risk Difference (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 8 Cirrhosis | 6 | 234 | Risk Difference (M‐H, Fixed, 95% CI) | 0.00 [‐0.09, 0.10] |
| 8.1 Parenteral nutrition | 0 | 0 | Risk Difference (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 8.2 Enteral nutrition | 3 | 116 | Risk Difference (M‐H, Fixed, 95% CI) | 0.03 [‐0.11, 0.17] |
| 8.3 Supplements | 3 | 118 | Risk Difference (M‐H, Fixed, 95% CI) | ‐0.02 [‐0.15, 0.10] |
| 9 HCC | 2 | 317 | Risk Difference (M‐H, Fixed, 95% CI) | 0.02 [‐0.03, 0.06] |
| 9.1 Parenteral nutrition | 0 | 0 | Risk Difference (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 9.2 Eneral nutrition | 0 | 0 | Risk Difference (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 9.3 Supplements | 2 | 317 | Risk Difference (M‐H, Fixed, 95% CI) | 0.02 [‐0.03, 0.06] |
| 10 Abstracts excluded | 9 | 491 | Risk Difference (M‐H, Fixed, 95% CI) | 0.02 [‐0.02, 0.07] |
| 10.1 Parenteral nutrition ‐ medical trials | 0 | 0 | Risk Difference (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 10.2 Parenteral nutrition ‐ surgical trials | 1 | 124 | Risk Difference (M‐H, Fixed, 95% CI) | 0.02 [‐0.03, 0.06] |
| 10.3 Enteral nutrition ‐ medical trials | 3 | 121 | Risk Difference (M‐H, Fixed, 95% CI) | 0.09 [‐0.04, 0.21] |
| 10.4 Enteral nutrition ‐ surgical trials | 0 | 0 | Risk Difference (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 10.5 Supplements ‐ medical trials | 4 | 202 | Risk Difference (M‐H, Fixed, 95% CI) | ‐0.00 [‐0.08, 0.07] |
| 10.6 Supplements ‐ surgical trials | 1 | 44 | Risk Difference (M‐H, Fixed, 95% CI) | 0.00 [‐0.12, 0.13] |
| 11 Surgical trials without transplant patients (no trials with transplant patients) | 2 | 168 | Risk Difference (M‐H, Fixed, 95% CI) | 0.01 [‐0.03, 0.06] |
| 11.1 Parenteral nutrition | 1 | 124 | Risk Difference (M‐H, Fixed, 95% CI) | 0.02 [‐0.03, 0.06] |
| 11.2 Enteral nutrition | 0 | 0 | Risk Difference (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 11.3 Supplements | 1 | 44 | Risk Difference (M‐H, Fixed, 95% CI) | 0.00 [‐0.12, 0.13] |
| 12 Intent to treat ‐ best‐case scenario for intervention | 11 | 838 | Risk Difference (M‐H, Fixed, 95% CI) | ‐0.05 [‐0.09, ‐0.01] |
| 12.1 Parenteral nutrition ‐ medical trials | 0 | 0 | Risk Difference (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 12.2 Parenteral nutrition ‐ surgical trials | 1 | 150 | Risk Difference (M‐H, Fixed, 95% CI) | ‐0.19 [‐0.28, ‐0.09] |
| 12.3 Enteral nutrition ‐ medical trials | 4 | 184 | Risk Difference (M‐H, Fixed, 95% CI) | 0.05 [‐0.07, 0.16] |
| 12.4 Enteral nutrition ‐ surgical trials | 0 | 0 | Risk Difference (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 12.5 Supplements ‐ medical trials | 5 | 454 | Risk Difference (M‐H, Fixed, 95% CI) | ‐0.03 [‐0.08, 0.01] |
| 12.6 Supplements ‐ surgical trials | 1 | 50 | Risk Difference (M‐H, Fixed, 95% CI) | ‐0.08 [‐0.23, 0.07] |
| 13 Intent‐to‐treat ‐ worst‐case scenario for intervention | 11 | 838 | Risk Difference (M‐H, Fixed, 95% CI) | 0.09 [0.05, 0.13] |
| 13.1 Parenteral nutrition ‐ medical trials | 0 | 0 | Risk Difference (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 13.2 Parenteral nutrition ‐ surgical trials | 1 | 150 | Risk Difference (M‐H, Fixed, 95% CI) | 0.16 [0.07, 0.25] |
| 13.3 Enteral nutrition ‐ medical trials | 4 | 184 | Risk Difference (M‐H, Fixed, 95% CI) | 0.09 [‐0.02, 0.20] |
| 13.4 Enteral nutrition ‐ surgical trials | 0 | 0 | Risk Difference (M‐H, Fixed, 95% CI) | 0.0 [0.0, 0.0] |
| 13.5 Supplements ‐ medical trials | 5 | 454 | Risk Difference (M‐H, Fixed, 95% CI) | 0.05 [0.00, 0.10] |
| 13.6 Supplements ‐ surgical trials | 1 | 50 | Risk Difference (M‐H, Fixed, 95% CI) | 0.16 [‐0.01, 0.33] |