Table 2.
Markers of inflammation and muscle damage after marathon race.
| Before | After | 1 day after | 3 days after | 15 days after | |
|---|---|---|---|---|---|
| Myoglobin (ng/ml) | 46 ± 50 | 1047 ± 702** | 184 ± 157** | 69 ± 104 | 71 ± 149 |
| LDH (U/L) | 480 ± 104 | 955 ± 267** | 681 ± 174** | 606 ± 147** | 517 ± 139 |
| CK (U/L) | 286 ± 735 | 679 ± 1151** | 2070 ± 2012** | 915 ± 1670* | 461 ± 1985 |
| CK-MB (µg/L) | 1.7 ± 1.8 | 4.9 ± 3.7** | 13.2 ± 13.7** | 3.3 ± 2.4* | 2.3 ± 1.5* |
| AST (U/L) | 36 ± 12 | 51 ± 20** | 93 ± 53** | 65 ± 36** | 39 ± 36 |
| ALT (U/L) | 39 ± 12 | 43 ± 14* | 48 ± 14** | 52 ± 17** | 48 ± 23* |
| Troponin (ng/ml) | 0.02 ± 0.01 | 0.09 ± 0.02* | 0.03 ± 0.05 | 0.02 ± 0.02 | 0.02 ± 0.01 |
| Pro BNP (pg/ml) | 38 ± 24 | 115 ± 90* | 90 ± 54** | 48 ± 36* | 41 ± 24 |
| IL-6 (pg/ml) | 3.1 ± 2.1 | 16.3 ± 16.2** | 3.7 ± 2 | 4.1 ± 1.8 | ND |
| IL-8 (pg/ml) | 4.4 ± 2 | 7.9 ± 7.5* | 4.5 ± 1.5 | 5.5 ± 8.1 | ND |
| IL-1β (pg/ml) | 4.6 ± 0.3 | 8.6 ± 6.3** | 5.3 ± 2.4 | 5.2 ± 2 | ND |
| IL-10 (pg/ml) | 3 ± 1 | 8.6 ± 7.1** | 3.2 ± 1.1 | 3.6 ± 2.2 | ND |
| TNF-α (pg/ml) | 4.9 ± 4.1 | 4.9 ± 4.3 | 5.1 ± 5.3 | 5.2 ± 5 | ND |
| IL-12p70 (pg/ml) | 3 ± 2.3 | 5 ± 6.2 | 3 ± 2.3 | 3.3 ± 2.6 | ND |
| Leukocytes (×103mm3) | 6 ± 1.3 | 15.5 ± 3.4** | 7.2 ± 1.6** | 5.5 ± 1 | 6 ± 1.4 |
| Neutrophils | 3.4 ± 1 | 13.4 ± 3.3** | 4.6 ± 1.3** | 3.1 ± 0.8 | 3.6 ± 1 |
| Monocytes | 0.4 ± 0.1 | 0.7 ± 0.4** | 0.5 ± 0.2** | 0.35 ± 0.1 | 0.35 ± 0.1 |
| Lymphocytes | 2 ± 0.5 | 1.3 ± 0.5** | 1.9 ± 0.5 | 1.8 ± 0.4 | 1.9 ± 0.5 |
LDH, lactate dehydrogenase; CK, creatine kinase; ALT, alanine transaminase; AST, aspartate transaminase; NT-BNP, N terminal pro-B-type natriuretic peptide; ND, not determined; IL, interleukin; TNF, Tumor necrosis factor. Values are means ± SD of 81 runners. *P < 0.05 vs. before the race; **p < 0.0001 vs. before the race.