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. 2019 Nov 1;6(4):041110. doi: 10.1117/1.NPh.6.4.041110

Table 1.

Summary of all the study subjects.

  Ungradable Gradable P value
Training and primary validation dataset
No. of SDOCT volumes 1353 4246
No. of subjects 260 549
Gender (male/female) 139/121 229/320 0.002
Age, years (mean±SD) 63.2±15.8 57.0±17.1 0.003
No. of eyes 402 1077
Eye (right/left) 222/180 533/544 0.050
External validation dataset 1 (PWH)
No. of SDOCT volumes 181 530
No. of subjects 80 227
Gender (male/female) 50/30 102/125 0.009
Age, years (mean±SD) 73.6±10.5 68.3±11.9 0.367
No. of eyes 122 387
Eye (right/left) 60/62 204/183 0.497
External validation dataset 2 (TMEC)
No. of SDOCT volumes 60 238
No. of subjects 42 158
Age, years (mean±SD) 61.7±14.5 60.7±12.4 0.177
Gender (male/female) 23/19 77/81 0.603
No. of eyes 60 234
Eye (right/left) 35/25 114/120 0.185

Note: OCT, optical coherence tomography; SD, standard deviation.

Unpaired t-test for numerical data and chi-square test for categorical data were used for comparison between ungradable and gradable groups. All the hypotheses tested were two-sided, and p-value <0.05 were considered to be significant which were values in bold.