Figure 2.

5‐ALA/SFC increased HO‐1 and Nrf2 expression in mProx24 cells. (A) Effect of 5‐ALA/SFC on HO‐1 production in kidney cells. HO‐1 expression increased on 5‐ALA and SFC exposure but did not change after CsA (30 μg·mL⁻¹) treatment in mProx24 cells for 24 h (n = 3; **P < 0.01). (B) Nrf2 expression (FITC) after 5‐ALA/SFC treatment for 24 h. Data are shown as the percentage of Nrf2‐positive cells (scale bar is 200 μm; n = 3; *P < 0.05, **P < 0.01). The data represent mean ± SD. Statistical significance was measured by Student's t‐test. Correlations were determined by Spearman's ranking.