Table 2.
Linear mixed model results for regional AIs that survived multiple comparisons correction in the primary analysis
AI region | N cases/controls | t value diag | t value age | t value sex | P value diag | P value age | P value sex | Cohen’s d (95% CI) |
---|---|---|---|---|---|---|---|---|
Fusiform thickness | 1704/1767 | 3.20 | −0.17 | 2.06 | 0.001 | 0.862 | 0.040 | 0.109 (0.04,0.18) |
Inferior temporal thickness | 1703/1768 | 2.97 | 0.07 | 0.73 | 0.003 | 0.948 | 0.467 | 0.102 (0.03,0.17) |
Isthmus cingulate thickness | 1699/1769 | −2.58 | 2.81 | 1.02 | 0.010 | 0.005 | 0.310 | −0.088 (−0.16,−0.02) |
Medial orbitofrontal thickness | 1705/1769 | −3.47 | 4.23 | −0.31 | 0.001 | 2.36 · 10−5 | 0.758 | −0.119 (−0.19,−0.05) |
Rostral anterior cingulate thickness | 1700/1765 | −3.37 | −0.69 | 1.45 | 0.001 | 0.491 | 0.147 | −0.116 (−0.18,−0.05) |
Rostral middle frontal thickness | 1707/1769 | −2.94 | −2.87 | 1.47 | 0.003 | 0.004 | 0.141 | −0.101 (−0.17,−0.03) |
Superior frontal thickness | 1706/1771 | −3.92 | 0.48 | −1.38 | 8.86 · 10−5 | 0.630 | 0.169 | −0.134 (−0.2,−0.07) |
Lateral orbitofrontal surface area | 1701/1762 | −3.28 | 0.81 | −0.07 | 0.001 | 0.421 | 0.946 | −0.112 (−0.18,−0.05) |
Medial orbitofrontal surface area | 1704/1763 | 3.17 | −0.27 | −0.87 | 0.002 | 0.787 | 0.385 | 0.109 (0.04,0.18) |
Putamen | 1712/1763 | 3.40 | 5.03 | 1.77 | 0.001 | 5.21·10−7 | 0.076 | 0.116 (0.05,0.18) |