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. 2019 Oct 31;6:250. doi: 10.1038/s41597-019-0216-1

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Overview of responses on the transcriptomics level (microarray data). Heatmap showing hierarchical clustering of transcriptome microarray samples using the Pearson correlation coefficient (PCC) as a distance measure, without reordering. High similarities can be observed between similar biological conditions and three biological conditions (heatmap diagonal). Actual PCC values were all higher than 0.85, even for the samples colored in blue (n = 118).