Fig. 4.

NDH-2 is essential for growth with fatty acids. Growth with (a) or without fatty acids (b). Data are representative of two independent experiments. c Growth and survival in the Wayne model of hypoxia. Data are averages of six to eight data points from two independent experiments. Growth and persistence in lungs (d) and spleens (e) of C57BL/6 mice. Data are averages from four mice per time point and representative of two independent infections. Error bars correspond to standard deviation. “Comp” stands for complemented. Statistical significance was assessed by one-way ANOVA followed by post hoc test (Tukey test; GraphPad Prism). Differences between strains in (d) and (e) are not significant. ***P < 0.001; ****P < 0.0001. Source data are provided as a Source Data file