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. 2019 Oct 31;9:15752. doi: 10.1038/s41598-019-51775-9

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Anti-apoptotic effects of AdMSCs on salivary glands. (A) TUNEL analysis image at 16 weeks after AdMSC transplantation. (B) Quantified TUNEL positive apoptotic cells count. The number of apoptotic cells in RI + PBS sham group is higher than that of RI+AdMSCs and PBS sham group. Results are presented as means ± SEMs. One-way ANOVA, Tukey’s post hoc multiple comparison test. (*Compare to PBS sham ^#compare to RI + PBS treated, *p < 0.05). Abbreviation: AdMSC, adipose-derived mesenchymal stem cells; PBS, phosphate-buffered saline; RI, radioiodine; TUNEL,Terminal deoxynucleotidyl transferase dUTP nick end labeling.