Figure 1.

Network connectivity shows functional interaction between investigated genes and other genes associated with intrinsic apoptotic signaling pathway. P53, Mcl-1 and CDKN1 (P21) have a direct association regarding physical interactions, co-expression and signaling pathway. In each cluster network, display-colored lines indicate a direct link, blue lines indicate the link provided by the pathway, pink lines represent the physical interactions, and purple lines show interactions with co-expression. Pink circle labels the genes involved in intrinsic apoptotic signaling pathway