Table 2.

Docking scores of tamoxifen, CA and GA into ER-α

Compounds	s-score a (kcal/mol)	Ki b	H-bond interaction
Tamoxifen	-11.21	61 nM	Arg-394, Glu-353
Caffeic acid	-4.47	524 nM	Arg Arg-394, 2H-Glu353
Gallic acid	-4.2	933 nM	Arg-394, Glu-353, Leu-346

^a S-score: binding free energy.

^b Ki = e ^ΔG/RT, R = 1.986 cal/mol.K, T = 298 K