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. 2019 Oct 31;9:15761. doi: 10.1038/s41598-019-52339-7

Figure 1.

Figure 1

SCD1 deficiency activates mTORC1 signaling. (A) 10 weeks old male WT and SCD1 GKO mice were fed HCD for 10 days. Western blot with the indicated antibodies performed on liver samples. (B) 10 weeks old male LOX and LKO mice were fed HCD for 10 days. Western blot with the indicated antibodies performed on liver samples. The relative phosphorylation levels of mTOR-Ser 2448 was quantified and normalized to total mTOR using densitometry. Values are mean ± SEM (n = 3/group), *P < 0.05 vs LOX counterparts by student’s two-tailed t test.