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. 2019 Oct 25;7:248. doi: 10.3389/fcell.2019.00248

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Copyright © 2019 Knebel, Fahlbusch, Dille, Wahlers, Hartwig, Jacob, Kettel, Schiller, Herebian, Koellmer, Lehr, Müller-Wieland and Kotzka.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Metabolic characterization of C57Bl6 and of alb-SREBP-1c mice at the age of 24 weeks used in the study. Data are expressed as mean ± SD (n = 8 of each phenotype). ^∗p < 0.05, ^∗∗p < 0.01, by Student’s t-test. Abbreviations: ALT, alanine transaminase; AST, aspartate transaminase; FFA, free fatty acids; GLDH, glutamate dehydrogenase; HOMA-IR, Homeostatic model assessment of insulin resistance; HOMA-ß Homeostatic model assessment of ß-cell function (%); TFA, total fatty acids; WAT, white adipose tissue.