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. 2019 Oct 25;7:248. doi: 10.3389/fcell.2019.00248

FIGURE 5.

FIGURE 5

Hepatic lipid composition of C57Bl6 and alb-SREBP-1c mice at the age of 24 weeks. (A) Fractional composition of liver TFAs and %-change within C57Bl6 and alb-SREBP-1c mice. (B) From the hepatic lipid composition, the sums of non-saturated FA, non-essential FA (C16:0 + cC16:1 + C18:0 + cC18:1), monounsaturated FA, polyunsaturated FA, saturated FA, essential FA [cC18:2 + cC18:3) or elongation index (C18:0/C16:0)], de novo lipogenesis (DNL) index (C16:0/cC18:2), Δ5 desaturase index (cC18:2/cC20:4), Δ6 desaturase index (cC18:3/cC18:2), Δ9 desaturase index (cC16:1/C16:0), and Δ9 desaturase index (cC18:1/C18:0) were calculated. Data are expressed as mean ± SD (n = 8 of each genotype). ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.01, by Student’s t-test. Abbreviations: DNL, de novo lipogenesis; EFA, essential fatty acids; MUFA, monounsaturated fatty acids; NEFA, non-essential fatty acids; PUFA, polyunsaturated fatty acids; SFA, saturated fatty acids; TFA, total fatty acids; UFA, unsaturated fatty acids.