TABLE 5.
Top 10 identified gene ontology categories from PANTHER overrepresentation test of our eQTL analysis results, according to fold enrichment.
| Gene ontology biological process category | # Ref genes | # Genes | Expected | Fold enrichment | p-value |
| Negative regulation of viral process (GO:0048525) | 99 | 46 | 20.25 | 2.27 | 5.16e-03 |
| Regulation of viral genome replication (GO:0045069) | 94 | 42 | 19.23 | 2.18 | 3.95e-02 |
| Regulation of viral life cycle (GO:1903900) | 144 | 64 | 29.46 | 2.17 | 1.88e-04 |
| Negative regulation of multi-organism process (GO:0043901) | 180 | 75 | 36.82 | 2.04 | 1.68e-04 |
| Regulation of symbiosis, encompassing mutualism through parasitism (GO:0043903) | 231 | 92 | 47.25 | 1.95 | 3.77e-05 |
| Regulation of viral process (GO:0050792) | 202 | 80 | 41.32 | 1.94 | 4.64e-04 |
| Neutrophil activation (GO:0042119) | 496 | 188 | 101.46 | 1.85 | 3.76e-11 |
| Neutrophil activation involved in immune response (GO:0002283) | 487 | 184 | 99.62 | 1.85 | 9.77e-11 |
| Granulocyte activation (GO:0036230) | 501 | 189 | 102.49 | 1.84 | 4.86e-11 |
| Neutrophil degranulation (GO:0043312) | 483 | 182 | 98.8 | 1.84 | 1.72e-10 |
# Ref genes: the number of genes in the reference list that map to this particular annotation data category. #Genes: the number of genes in our eQTL analysis identified gene list that map to this annotation data category. Expected: the number of genes we would expect in our gene list for this category, based on the reference list. Fold enrichment: # Genes/Expected. p-value: Bonferroni-corrected p-value.