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. 2019 Oct 31;20(8):328. doi: 10.1208/s12249-019-1532-7

Table I.

Product Resistance Parameters According to Eq. 5 for Products Modeled Here

Product R0 A1 A2
× 104 m/s cm2 h Torr/g × 107 s−1 cm h Torr/g × 102 m−1 cm−1
5% mannitol (11) 6.72 1.4 7.68 16 0 0
5% povidone (11) 5.42 1.13 2.40 5 0 0
0.5% lysozyme at Tsh =  − 25 ° C (34) 2.23 0.4638 9.89 20.6 4.394 4.394
0.5% lysozyme at Tsh = 25 ° C (34) 5.98 1.2467 0 0 0 0
2% lysozyme at Tsh =  − 25 ° C (34) 3.98 0.829 7.76 16.16 2.386 2.386
2% lysozyme at Tsh = 25 ° C (34) 11.77 2.4518 0 0 0 0
0.5% BSA at Tsh =  − 25 ° C (34) 2.60 0.5429 9.94 20.7 4.951 4.951
0.5% BSA at Tsh = 25 ° C (34) 6.53 1.3601 0 0 0 0
2% BSA at Tsh =  − 25 ° C (34) 5.43 1.131 9.79 20.4 0.1019 0.1019
2% BSA at Tsh = 25 ° C (34) 14.61 3.043 0 0 0 0
0.5% IgG at Tsh =  − 25 ° C (34) 4.42 0.9204 5.23 10.9 1.349 1.349
0.5% IgG at Tsh = 25 ° C (34) 7.00 1.4582 0 0 0 0
2% IgG at Tsh =  − 25 ° C (34) 4.15 0.8646 10.79 22.49 1.716 1.716
2% IgG at Tsh = 25 ° C (34) 15.36 3.2 0 0 0 0
5% sucrose (22) 1.00 0.208 7.34 15.29 1.6 1.6