Effects of wRG, eRG, fRG, and ginsenoside Rd on IL-4 expression in PMA/A23187-induced RBL-2H3 cells. (A) Effects of wRG, eRG, and fRG. (B) Effects of ginsenoside Rd. RBL-2H3 cells were stimulated with PMA/A23187 in the presence of fRG, eRG, wRG (10mg/mL), or ginsenoside Rd (10 mM) for 18 h. Data are shown as box plots (n=4). Means with the same letters are not significantly different (p<0.05). eRG, ethanol-extracted RG; fRG, fermented RG; IL, interleukin; RG, red ginseng; Veh, vehicle;wRG, water-extracted RG.