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. 2019 Nov 1;19:275. doi: 10.1186/s12935-019-0958-z

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — PTP1B is highly expressed in human breast tissues and is positively correlated to UCA1 level. a The expression of PTP1B examined by IHC staining in human breast tissues exhibited a much higher expression in the tumor tissues than the normal peritumor tissues. b PTP1B expression measured by qRT-PCR also showed a significant higher expression in the tumor tissues than the normal peritumor tissues assay in human breast cancer tissues and their paired noncancerous tissues (p < 0.001 by Wilcoxon’s signed-rank test). c Pearson’s correlation analysis on PTP1B expression and UCA1 level based on qRT-PCR data in breast tumor tissues suggested a strong positive correlation, with a correlation coefficient of 0.8143 (p < 0.001, n = 35)