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A model shows how UCA1 promotes breast cancer by up-regulating the expression of the PTP1B oncogene via sequestration of miR-206. Without the presence of UCA1, MiR-206 is capable of inhibiting the expression of PTP1B through directly binding to the 3′-UTR of PTP1B mRNA. When UCA1 is present, UCA1 can sponge miR-206, leading to the increase of PTP1B expression and results in the promotion of breast cancer growth
