Table 2.

Bio-humoral characteristics of the clinical population

	Clinical population n = 539	Quartile I < 138 ng/L n = 135	Quartile II–III 138–264 ng/L n = 270	Quartile IV > 264 ng/L n = 134	P value
Renal
Creatinine, mg/dL	0.87 ± 0.23	0.91 ± 0.27	0.87 ± 0.22	0.86 ± 0.19	ns
Hepatic
AST, IU/L	24 ± 10	24 ± 11	24 ± 10	26 ± 9	0.0411
ALT, IU/L	21 ± 13	19 ± 11	21 ± 14	23 ± 13	0.0180
ALP, IU/L	51 ± 18	47 ± 17	49 ± 16	61 ± 20	< 0.0001
Metabolic (glucose)
FTP, mg/dL	112 ± 36	109 ± 30	116 ± 41	109 ± 29	ns
FTP ≥ 100 mg/dLa	339 (63)	82 (61)	174 (64)	83 (62)	ns
Insulin, μUI/mL	11.6 ± 11.0	13.3 ± 12.5	11.3 ± 10.1	10.3 ± 10.1	0.0345*
HOMA-IR index	3.5 ± 4.2	3.9 ± 4.5	3.5 ± 4.1	2.9 ± 3.2	0.0569*
Metabolic (lipid)
Total cholesterol, mg/dL	183 ± 49	171 ± 43	180 ± 45	201 ± 55	< 0.0001
LDL, mg/dL	106 ± 40	100 ± 37	104 ± 38	118 ± 45	0.0015
HDL, mg/dL	52 ± 17	46 ± 13	52 ± 15	61 ± 19	< 0.0001
HDL ≤ 40 mg/dL, male or HDL ≤ 50 mg/dL, femalea	160 (30)	60 (44)	81 (30)	19 (14)	< 0.0001
Total/HDL cholesterol	3.7 ± 1.1	3.8 ± 1.2	3.7 ± 1.2	3.5 ± 1.1	0.0193
Apo A1, mg/dL	143 ± 32	132 ± 32	143 ± 30	154 ± 34	< 0.0001
Apo B, mg/dL	87 ± 28	82 ± 28	87 ± 27	93 ± 29	0.0024
Lipoprotein (a)	21.3 ± 23.2	15.8 ± 18.2	21.7 ± 23.4	24.9 ± 26.3	0.0018
Triglicerides, mg/dL	124 ± 81	126 ± 84	127 ± 86	118 ± 68	ns
Triglyceride ≥ 150 mg/dLa	131 (24)	34 (25)	67 (25)	30 (23)	ns
Inflammatory and vascular
hs-CRP, mg/dL	0.40 ± 1.09	0.41 ± 0.61	0.38 ± 1.35	0.43 ± 0.81	ns
Interleukin 6, ng/L	1.35 ± 2.35	1.56 ± 2.71	1.27 ± 2.45	1.30 ± 1.67	ns
Adipokines
Adiponectin, μg/mL	9.8 ± 6.9	8.11 ± 5.1	9.98 ± 7.2	11.19 ± 7.6	0.0006
Leptin, ng/mL	9.93 ± 10.66	11.38 ± 13	9.16 ± 9	9.99 ± 10.98	ns

Continuous variables are presented as mean ± standard deviation

* I vs. IV quartile

^aCriteria of metabolic syndrome