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. 2019 Oct 31;18:144. doi: 10.1186/s12933-019-0949-3

Table 3.

Angiography imaging results relative to PCSK9 groups

CTA population (n = 412) Quartile I
< 136 ng/L
n = 103
Quartile II–III
136–266 ng/L
n = 206
Quartile IV
> 266 ng/L
n = 103
P value
Obstructive CAD at CTA
 Stenosis > 50% 144 (35) 40 (39) 71 (34) 33 (32) ns
 Stenosis > 70% 45 (11) 12 (12) 23 (11) 10 (10) ns
Coronary plaques
 Total N. of plaques 3.9 ± 3.8 4.36 ± 3.89 3.67 ± 3.77 3.37 ± 3.77 0.0621*
 N. of non-obstructive plaques 3.0 ± 3.1 3.33 ± 2.89 3.14 ± 3.10 2.42 ± 2.93 0.0322*
 N. of obstructive plaques 0.9 ± 1.7 0.94 ± 1.57 0.73 ± 1.42 0.85 ± 1.87 ns
 N. of calcified plaques 0.9 ± 1.7 0.85 ± 1.84 0.93 ± 1.69 0.81 ± 1.74 ns
 N. of mixed plaques 2.6 ± 3.2 3.14 ± 3.42 2.49 ± 3.12 2.19 ± 3.15 0.0356*
 N. of non-calcified plaques 0.5 ± 0.9 0.38 ± 0.85 0.54 ± 1.02 0.38 ± 0.72 ns
CTA score 12 ± 11 13.17 ± 11.53 11.83 ± 10.71 9.99 ± 11.11 0.0391*

Continuous variables are presented as mean ± standard deviation, categorical variables as absolute N and (%)

* I vs. IV quartile