Skip to main content
. 2019 Nov 1;20:219. doi: 10.1186/s13059-019-1831-z

Table 6.

Regression analyses relating genera with obesity, birthplace, and age at relocation to the mainland USA. After individually examining the associations of 74 genera with relative abundance > 0.01% with obesity and with birthplace/age at relocation to the mainland USA, the ten genera displayed in this table were found to be overlapping between these two analyses. Regression models for obesity adjusted for age, sex, and center, and regression models for birthplace and age at relocation adjusted for sex and center

Association with obesity Association with birthplace and age at relocation to USA Direction of association
P value P value P value P value
Beta Unadj FDR adj Beta Unadj FDR adj Obesity Early-life exposure to USA Consistent?
Oscillospira − 0.139 < 0.001 < 0.001 − 0.071 0.003 0.0111 Negative Positive No
Unclassified.Clostridiales − 0.207 < 0.001 < 0.001 0.101 < 0.001 < 0.001 Negative Negative Yes
Unclassified.Ruminococcaceae − 0.138 < 0.001 < 0.001 0.067 0.005 0.016818 Negative Negative Yes
Unclassified.Christensenellaceae − 0.426 < 0.001 < 0.001 0.158 0.003 0.0111 Negative Negative Yes
Unclassified.Coriobacteriaceae − 0.235 < 0.001 < 0.001 0.137 0.001 0.0056923 Negative Negative Yes
Megasphaera 0.277 < 0.001 < 0.001 − 0.167 0.003 0.0111 Positive Positive Yes
Acidaminococcus 0.318 < 0.001 < 0.001 − 0.3 < 0.001 < 0.001 Positive Positive Yes
Anaerotruncus − 0.18 < 0.001 < 0.001 − 0.083 0.011 0.03256 Negative Positive No
Unclassified.Victivallaceae − 0.144 0.009 0.037 0.118 0.004 0.014095 Negative Negative Yes
Unclassified.YS2 − 0.217 0.004 0.0185 0.205 < 0.001 < 0.001 Negative Negative Yes