Table 6.

Multivariate cox regression analysis of DFS: Budding evaluated on H&E

	Disease-free survival
Parameter	HR	95% CI	P
Positive Budding H&E	2.34	[1.14; 4.79]	0.020
Higher ypT stage [ypT3–4]	2.85	[1.16; 7.02]	0.023
ypN+	1.34	[0.63; 2.83]	0.449