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. 2019 Nov 1;11:53. doi: 10.1186/s13099-019-0335-4

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Clusters of orthologous group (COG) analysis of RstA-regulated genes in EHEC O157. Bars represent the number of up-regulated (blue) or down-regulated (orange) genes in the ΔrstA mutant compared to those in the EHEC O157 WT strain. The significant enrichment of a given COG in the sets of up- or downregulated genes was determined using one-tailed Fisher’s exact test with Benjamini–Hochberg false discovery rate correction