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. 2019 Nov 1;15:386. doi: 10.1186/s12917-019-2118-z

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Timeline of the study. Cartilage samples were collected and let to equilibrate in media for 48 h before the commencement of the experiment. Then, at day 0 and 4 samples were exposed to IL-1β and PL. All the other days of the experiment explants received full growth media only. Media was collected every-2 days and at the end of the study, cartilage and media samples were collected