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. 2019 Oct 24;25:7966–7975. doi: 10.12659/MSM.918951

Figure 1.

Figure 1

Comparison of the findings in the three groups of apolipoprotein E-deficient (ApoE−/−) mice, the untreated Control group, the streptozotocin-treated diabetic model (the STZ group), and the dimethyl fumarate-treated diabetic model (the DMF+STZ group). (A) Photomicrograph of the histology of the thoracic aorta in the Control group, the STZ group, and the DMF+STZ group. Hematoxylin and eosin (H&E). Magnification ×40. (B) The plaque area of the thoracic aorta (μm2) in the Control group, the STZ group, and the DMF+STZ group, expressed as the mean±standard deviation (SD). * P<0.05 compared with the Control group. # P<0.05 compared with the STZ group. (C) The gp91phox protein in the thoracic aorta in the Control group, the STZ group, and the DMF+STZ group, detected by Western blot. (D) Quantitative analysis results of gp91phox protein expression, expressed as the mean ± standard deviation (SD). * P<0.05 compared with the Control group. # P<0.05 compared with the STZ group. (E) Nuclear factor-κB (NF-κB) and intercellular adhesion molecule 1 (ICAM-1) protein expression in the thoracic aorta in the Control group, the STZ group, and the DMF+STZ group, detected by Western blot.