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. 2019 Oct 24;25:7966–7975. doi: 10.12659/MSM.918951

Figure 2.

Figure 2

Comparison of the expression of nuclear factor erythroid 2-related factor 2 (Nrf2) and nitric oxide synthases (NOS) in the three groups of apolipoprotein E-deficient (ApoE−/−) mice, the untreated Control group, the streptozotocin-treated diabetic model (the STZ group), and the dimethyl fumarate-treated diabetic model (the DMF+STZ group). (A) Nuclear factor erythroid 2-related factor 2 (Nrf2) protein in the thoracic aorta of the Control group, the STZ group, and the DMF+STZ group detected using Western blot. (B) Quantitative analysis of Nrf2 protein expression in the Control group, the STZ group, and the DMF+STZ group, expressed as the mean±standard deviation (SD). # P<0.05 compared with the STZ group. (C) Endothelial nitric oxide synthase (eNOS) and phosphorylated eNOS (p-eNOS) proteins in the thoracic aorta in the Control group, the STZ group, and the DMF+STZ group, detected using Western blot. (D) Quantitative analysis of the p-eNOS and eNOS, expressed as the mean±standard deviation (SD). * P<0.05 compared with the Control group. # P<0.05 compared with the STZ group.