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. 2019 Oct 24;25:7966–7975. doi: 10.12659/MSM.918951

Figure 3.

Figure 3

Comparison of the expression of gp91phox and nuclear factor erythroid 2-related factor 2 (Nrf2) in human umbilical vein endothelial cells (HUVECs) in the normal control (NC) group, the high glucose (HG) group, the dimethyl fumarate and high glucose (DMF+HG) group, and the DMF+HG+Nrf2−/− group. (A) Quantitative results of nicotinamide-adenine dinucleotide phosphate (NADPH) oxidase subunit gp91phox activity in HUVECs in the NC group, the HG group, the DMF+HG group, and the DMF+HG+Nrf2−/− group, expressed as the mean ± standard deviation (SD). * P<0.05 compared with the NC group. # P<0.05 compared with the HG group. @ P<0.05 compared with the DMF+HG group. (B) Nuclear factor erythroid 2-related factor 2 (Nrf2) protein expression in HUVECs in the NC group, the HG group, the DMF+HG group, and the DMF+HG+Nrf2−/− group, detected using Western blot. (C) Quantitative analysis of Nrf2 protein expression in the NC group, the HG group, the DMF+HG group, and the DMF+HG+Nrf2−/− group, expressed as the mean ± standard deviation (SD). * P<0.05 compared with the NC group. # P<0.05 compared with the HG group. @ P<0.05 compared with the DMF+HG group.