Table 2. Model-Based Measurement Estimates .
| Variable | Adjustment | Fixed Effects | IRR or OR (95% CI)a | P Value |
|---|---|---|---|---|
| Incidence models | ||||
| Community-acquired CDI | Unadjusted | Time, mo | 1.007 (1.001-1.013) | .01 |
| Adjusted | Time, mo | 1.004 (0.999-1.009) | .14 | |
| Setting, urban relative to rural | 0.862 (0.623-1.193) | .37 | ||
| Type, academic vs community | 0.999 (0.738-1.352) | .99 | ||
| Test type (NAAT vs antigen) | 1.919 (1.653-2.228) | <.001 | ||
| Health care facility–associated CDI | Unadjusted | Time, mo | 0.998 (0.993-1.004) | .49 |
| Adjusted | Time, mo | 0.995 (0.990-0.999) | .03 | |
| Setting, urban vs rural | 0.802 (0.631-1.020) | .07 | ||
| Type, academic vs community | 1.026 (0.823-1.278) | .82 | ||
| Test type, NAAT vs antigen | 1.831 (1.591-2.108) | <.001 | ||
| Community-acquired NAP1 strain of CDI | Unadjusted | Time, mo | 1.007 (0.994-1.021) | .31 |
| Health care facility–associated NAP1 strain of CDI | Unadjusted | Time, mo | 1.011 (0.990-1.032) | .32 |
| Proportion model | ||||
| Community-acquired CDI as proportion of total CDI cases | Unadjusted | Time, mo | 1.010 (1.006-1.015) | <.001 |
| Adjusted | Time, mo | 1.010 (1.006-1.014) | <.001 | |
| Setting, urban vs rural | 1.056 (0.815-1.369) | .68 | ||
| Type, academic vs community | 0.847 (0.674-1.065) | .16 | ||
| Test type, NAAT vs antigen | 1.083 (0.904-1.296) | .39 |
Abbreviations: CDI, Clostridioides difficile infection; IRR, incidence rate ratio; NAAT, nucleic acid amplification testing; OR, odds ratio.
a
Values are IRRs for incidence models and OR for proportion model.