Table. Characteristics of Patients With Idiopathic Subglottic Stenosis.
| Characteristic | ED (n = 603) | ERMT (n = 121) | CTR (n = 86) | Total (N = 810) | Effect Sizea | Test Typeb |
|---|---|---|---|---|---|---|
| Age at index procedure, median (IQR), y | 49 (42-57) | 56 (48-63) | 48 (39-55) | 50 (43-58) | 0.036 (0.015-0.063) | 1 |
| Female, No. (%) | 593 (98.3) | 121 (100) | 84 (97.5) | 798 (98.5) | 0.032 (0-0.089) | 2 |
| Married, No. (%)c | 426 (76.1) | 86 (76.1) | 70 (86.4) | 582 (77.2) | 0.076 (0-0.141) | 2 |
| White race, No. (%) | 580 (95.9) | 121 (100) | 86 (100) | 787 (97.2) | 0.105 (0.017-0.171) | 2 |
| White (non-Hispanic or Latino) ethnicity, No. (%)c | 503 (97.4) | 87 (100) | 60 (93.8) | 650 (97.5) | 0.089 (0-0.159) | 2 |
| Educational level, No. (%)c | ||||||
| Graduate school | 153 (27.4) | 22 (19.5) | 14 (17.3) | 189 (25.1) | 0.092 (0-0.127) | 2 |
| College graduate | 218 (39.0) | 42 (37.2) | 38 (46.9) | 298 (39.6) | ||
| Some college | 118 (21.0) | 34 (30.1) | 23 (28.4) | 175 (23.3) | ||
| High school or less | 70 (12.5) | 15 (13.3) | 5 (6.2) | 90 (12.0) | ||
| Stenosis, median (IQR), % | 50 (40-70) | 75 (64-80) | 60 (60-70) | 60 (50-75) | 0.06 (0.034-0.088) | 1 |
| Stenosis length, median (IQR), mm | 12 (10-17) | 15 (10-20) | 17 (15-20) | 15 (10-20) | 0.02 (0.005-0.042) | 1 |
| Distance below glottis, median (IQR), mm | 15 (10-20) | 10 (5-15) | 10 (5-15) | 11 (8-17) | 0.018 (0.005-0.04) | 1 |
| Disease duration, median (IQR), y | 5.5 (2.5-9.9) | 8.6 (3.4-13.0) | 6.1 (3.9-10.2) | 5.8 (2.6-10.7) | 0.014 (0.002-0.034) | 1 |
| Surgical procedure, No. (range) | 3 (2-7) | 3 (2-6) | 5 (3-7) | 3 (2-7) | 0.015 (0.004-0.031) | 1 |
| Charlson Comorbidity Index, median (IQR) | 0 | 0 | 0 | 0 | 0.007 (0-0.018) | 1 |
| Gastroesophageal reflux disease, No. (%)c | 206 (37.1) | 43 (38.4) | 31 (38.8) | 280 (37.5) | 0.013 (0-0.05) | 2 |
| Premenopausal, No. (%)c | 204 (72.6) | 20 (64.5) | 25 (71.4) | 249 (72.0) | 0.051 (0-0.138) | 2 |
| Hormone replacement therapy, No. (%)c | 5 (1.8) | 1 (3.2) | 0 | 6 (1.7) | 0.054 (0-0.143) | 2 |
| Full-term pregnancy, No. (%) | ||||||
| 0 | 139 (25.3) | 12 (10.9) | 13 (16.5) | 164 (22.2) | 0.123 (0.041-0.157) | 2 |
| 1 | 81 (14.7) | 10 (9.1) | 7 (8.9) | 98 (13.3) | ||
| 2 | 203 (36.9) | 51 (46.4) | 35 (43.8) | 289 (39.1) | ||
| 3 | 88 (16.0) | 22 (20.0) | 16 (20.0) | 126 (17.1) | ||
| >3 | 39 (7.1) | 15 (13.6) | 8 (10.0) | 62 (8.4) | ||
| Years of follow-up, median (IQR), y | 1.3 (0.4-2.2) | 1.5 (0.2-3.6) | 4.3 (1.7-6.1) | 1.4 (0.4-2.5) | 0.011 (0.002-0.024) | 1 |
Abbreviations: CTR, cricotracheal resection; ED, endoscopic dilation; ERMT, endoscopic resection with adjuvant medical therapy; IQR, interquartile range.
a
Epsilon-squared for Kruskal-Wallis test and Cramer V for Pearson χ2 test. The 95% CIs for epsilon-squared values are estimated by adjusted bootstrap percentile (bias-corrected and accelerated) interval with 1000 replications; 95% CIs for Cramer V values are estimated by noncentral χ2.
b
Test type: 1, Kruskal-Wallis test; 2, Pearson χ2 test.
c
Not reported for all participants.