Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Different external and internal environmental stimuli (nutrition/metabolism, light/circadian clocks, endocrine disruptors) are envisioned to affect the timing and progression of puberty by altering the counteractive activity of PcG/TrxG-mediated epigenetic machinery. According to this model the different stimuli depicted can affect the time of puberty by modifying the function of either the PcG or TrxG complex or both.
