Table 1.
Quantitative ultrasound: Optimal cutoffs obtained using proton density fat fraction with magnetic resonance imaging as the reference standard
Technique | S0 vs S1–S3 | S0–S1 vs S2–S3 | S0–S2 vs S3 |
BSC[20], 1/cm-sr (NAFLD) | 0.0038 | --------- | --------- |
Sensitivity: 93% | --------- | --------- | |
Specificity: 97% | --------- | --------- | |
CAP[30], dB/m (NAFLD) | 288 | --------- | --------- |
Sensitivity: 75% | |||
Specificity: 77% | |||
ATI[40], dB/cm/MHz (NAFLD) | 0.63 | 0.72 | --------- |
Sensitivity: 80% | Sensitivity: 100% | --------- | |
Specificity: 89% | Specificity: 78% | --------- | |
UGAP[43], dB/cm/MHz (NAFLD) | 0.63 | 0.68 | 0.74 |
Sensitivity: 80% | Sensitivity: 83% | Sensitivity: 87% | |
Specificity: 91% | Specificity: 74% | Specificity: 79% | |
SSE[46], mm/μs (not specified) | 1.537 | 1.511 | --------- |
Sensitivity: 80% | Sensitivity: 100% | --------- | |
Specificity: 86% | Specificity: 96% | --------- |
In parenthesis: Etiology of liver disease. BSC: Backscatter coefficient; sr: Square radian; CAP: Controlled attenuation parameter; dB: Decibel; ATI: Attenuation imaging; MHz: Megahertz; UGAP: Ultrasound guided attenuation parameter; SSE: Sound speed estimation; NAFLD: Non-alcoholic fatty liver disease.