Figure 5.

Validation of IFNs effect on EC. (A) Number share and unique genes induced by IFN-α on ECs (20) and leukocyte- mediators after blocking of both IL-1 and TNF-α on ECs. (B–D) Protein levels of IFN-α downstream genes: CXCL11 and TRAIL, and IFN-gamma produced by stimulated leukocytes (before the dash line) and EC (after the dash line) in the supernatants, measured by Olink®. Data are shown as mean (SD), represented for two independent experiments. Colors correlate to three donors of whom PBMCs were isolated.