TABLE 1.
Statistics of simple linear regression analyses performed between different morphological parameters and IL-1β relative intensity of a population of activated microglial cells.
| Parameter | F | P significance | Regression line | r2 |
| Cell perimeter | 40.3 | 3.7 × 10–9 | Y = −0.68X + 1195 | 0.245∗∗∗ |
| Cell circularity | 37.9 | 9.5 × 10–9 | Y = −1 × 10–5X + 0.007 | 0.234∗∗∗ |
| Mean radius | 37.1 | 1.3 × 10–8 | Y = −0.017X + 3 | 0.231∗∗∗ |
| Convex hull perimeter | 36.1 | 1.9 × 10–8 | Y = −0.093X + 222 | 0.226∗∗∗ |
| Bounding circle diameter | 34.7 | 3.5 × 10–8 | Y = −0.036X + 88 | 0.212∗∗∗ |
| Max span convex hull | 32.5 | 8.4 × 10–8 | Y = −0.035X + 87 | 0.209∗∗∗ |
| Roughness | 32.2 | 9.3 × 10–8 | Y = −1.3 × 10–3X + 5.4 | 0.206∗∗∗ |
| Convex hull area | 29.3 | 3.1 × 10–7 | Y = −2.26X – 3186 | 0.191∗∗∗ |
| Density | 26.7 | 9.2 × 10–7 | Y = −2 × 10–4X + 0.3 | 0.177∗∗∗ |
| Cell area | 18.9 | 2.9 × 10–5 | Y = −0.48X + 953 | 0.132∗∗∗ |
| Lacunarity | 14.3 | 2.3 × 10–3 | Y = 8 × 10–5X + 0.44 | 0.104∗∗∗ |
| Fractal dimension | 9.1 | 0.003 | Y = 6 × 10–5X+ | 0.068∗∗ |
| The ratio convex hull radii | 1.7 | 0.19 | Y = 4 × 10–4X + 1.87 | 0.013 |
| Convex hull circularity | 0.7 | 0.39 | Y = −3 × 10–5X + 0.77 | 0.006 |
| Convex hull span ratio | 0.5 | 0.49 | Y = −1 × 10–4X + 1.73 | 0.004 |
Regression dependence by F-test procedure was significant when P < 0.05. Coefficient of determination (r2) was used as a measure of the strength of the straight-linear relationship (∗∗∗P < 0.001; ∗∗P < 0.005).