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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Hypertension. 2003 Oct 27;42(6):1164–1170. doi: 10.1161/01.HYP.0000100423.24330.96

Figure 3.

Figure 3.

Myocyte cross-sectional area (MCSA) and ICF in LV of sham-16W rats and 2K-1C-8W and 2K-1C-16W rats treated with vehicle or Ac-SDKP at 800 μg/kg per day. Green staining represents collagen. Eight weeks after clipping, LV collagen deposition and myocyte cross-sectional area were increased. LV collagen in 2K-1C/vehicle-8W was similar to 2K-1C/vehicle-16W. Ac-SDKP reversed the increase in LV collagen but not the increase in MCSA, suggesting that Ac-SDKP can reverse cardiac fibrosis but not hypertrophy in 2K-1C hypertensive rats.