Table.

Measurement of Systolic Blood Pressure, Organ Weight, and Plasma Ac-SDKP Concentration

			2K-1C
Parameters	Sham-8W	Sham-16W	Vehicle-8W	Vehicle-16W	Ac-SDKP (400 μg · kg−1 · d−1)	Ac-SDKP (800 μg · kg−1 · d−1)
SBP, mm Hg	123±7	112±3	208±7*	157±3†	149±3†	157±3†
LVW/BW, mg/100 g	179±4	168±4	263±23*	210±9†	211±8†	231±7†
RVW/BW, mg/100 g	51.4±2.2	45.2±1.6	56.3±3.6	46.9±1.5	50.2±2.1	48.8±3.5
AW/BW, mg/10 g	1.3±0.1	1.5±0.1	1.5±0.1	1.3±0.1	1.6±0.1	1.5±0.1
Plasma Ac-SDKP, nmol/L	3.93±0.30	3.55±1.12	3.92±0.54	2.17±0.20	5.77±1.39‡	13.19±3.69‡

SBP indicates systolic blood pressure; LVW, left ventricular weight; RVW, right ventricular weight; AW, atrial weight; BW, body wt.

^*P<0.05 vs sham-8W;

^†P<0.05 vs sham-16W;

^‡P<0.05 vs 2K-1C/vehicle-16W.