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Representative PV loops from 14-month-old WKY receiving vehicle (A), WKY receiving Ac-SDKP (B), SHR treated with vehicle (C), and SHR treated with Ac-SDKP (D). Although the EDPVR is steeper in SHR than in WKY, reflecting increased chamber stiffness in the hypertensive rats, treatment with Ac-SDKP did not change the slope of the EDPVR.
