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Dynamics of insulin (A, C, E) and C-peptide (B, D, F) secretion during the 2-step hyperglycemic clamps performed before (●) and after (□) treatments with exenatide (left), saline (middle), and saline in SHAM-operated (right) baboons. Number of baboons: 12 in exenatide group, 12 in saline group, and 4 in SHAM group. Comparisons between baseline and after-treatment data were performed by Wilcoxon’s test. *P < 0.05.
