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. 2019 May 2;36(6):1291–1303. doi: 10.1007/s12325-019-00957-y

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — Change in global TOP scores (%) from baseline (V1) to 6 months (V7) in the intervention and control groups. Within-group comparisons using Student’s paired t-test: *p < 0.05; ****p < 0.0001. Between-group comparisons using the ANOVA Fisher-Snedecor (p value)