Fig. 5.

LPA is associated with LDL from multiple human subjects and decreased by lipid-lowering drug therapy. A: Correlation between LPA associated with LDL isolated from human plasma and total plasma cholesterol. B: Correlation between LPA associated with LDL isolated from human plasma and LDL-associated cholesterol. In both cases, data (n = 17) were analyzed by linear regression with r² and P values reported in the figure. Representative data showing LPA levels from fractionated plasma collected prior to (C) or following (D) treatment with a statin. (n = 1) (see also Table 2). E: Measurement of cholesterol from fractionated human plasma collected prior to and after treatment with a statin (atorvastatin, 40 mg/day).