Fig. 5.

Effects of sinomenine (SIN) or/and cisplatin on gastric cancer cells invasion were evaluated by Transwell assay with Matrigel. HGC-27 cell lines were treated with SIN and/or cisplatin for 24 hours as above. (a) The number of cells that invaded through the membrane precoated with Matrigel was counted under a light microscope with 200C× magnification. (b) Bar graph of the relative number of invading cells in (a). *P < 0.05 versus control cells; #P < 0.05 versus 1 μg/mL cisplatin alone cells.