Table 1.

Delta systolic blood pressure (ΔSBP) in male and female mice.

Sex	Males				Females
Group	18-weeks WT	18-weeks HET	36-weeks WT	36-weeks HET	18-weeks WT	18-weeks HET	36-weeks WT	36-weeks HET
ΔSBP (mmHg)	−2.3 ± 1.5	25.1 ± 2.7	8.3 ± 7.0	19.2 ± 4.6	5.8 ± 4.1	−3.7 ± 4.8	−6.9 ± 3.1	−3.0 ± 4.8
Sample size (n)	18	21	12	11	21	27	29	25
P value (Paired t-test)	0.31	P < 0.00001	0.26	0.002	0.17	0.45	0.03	0.53
P value (WT vs HET, unpaired t-test)		P < 0.00001		0.21		0.14		0.5

ΔSBP was calculated as systolic blood pressure on a liberal salt diet minus systolic blood pressure on a restricted salt diet. Data represent mean ± S.E.M. Paired t-test (two-tailed) was used to assess the statistical significance of the ΔSBP individually within each of the eight cohorts. Unpaired t-test (two-tailed) was used to compare values of ΔSBP between WT and HET of the same sex and age.