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. 2019 Oct 24;27(6):503–513. doi: 10.4062/biomolther.2019.139

Table 2.

The major drug targets of some natural products

Induction of extracellular matrix degradation by matrix metalloproteinases
Compromised production of the extracellular matrix
The apoptosis and proliferation of chondrocytes
Inflammation and oxidative stress generated in articular tissues