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. 2019 Oct 11;47(5):1415–1427. doi: 10.1042/BST20190254

Scheme 1. Synthesis of 007-AM from 007.

Scheme 1.

007-AM may be prepared from 007 by the reaction of bromomethyl acetate with 007 in the presence of diisopropylethylamine in dimethylformamide to give 007-AM in 31% yield and 50:50 dr after 15 min at room temperature.